My firewall settings went bad causing GlassWire to repeatedly re-prompt and block apps. GlassWire was seeing everything as new and kept adding multiple rule entries in the Windows Firewall. Initially I blamed a Windows Update, but that was a red herring.
In the end I nuked the lot and started over with all my configuration. Whilst is useful to have the manual backup and restore steps it is rather clunky and hardly user friendly. This function really needs to wrapped up into a little utility.